MarginReality

Supplements E-commerce Benchmarks

Complete benchmark data for online supplement stores. All figures based on industry averages and aggregated Shopify merchant data.

Why these numbers look like this

Supplements combine strong 55% gross margins with a 14% net margin — one of the best net-to-gross ratios in e-commerce — because subscription models drive predictable repeat purchases and low 4% refund rates. The hidden cost is FDA compliance: label accuracy, third-party testing, and good manufacturing practices add 5-8% to COGS that most other industries don't face. Brands that nail compliance and retention simultaneously scale profitably because their CLV dwarfs the acquisition cost.

At a Glance

55%

Avg gross margin

14%

Avg net margin

3.5x

Avg ROAS

$32

Avg CAC

$55

Avg order value

$400

Avg CLV

Profit Margin

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Gross margin40–65%(avg 55%)
Net margin10–20%(avg 14%)
COGS25–45%(avg 35%)
Return on ad spend2.8–4.8x(avg 3.5x)
Ad cost % of revenue8–20%(avg 14%)

Customer Acquisition

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CAC$22–$48(avg $32)
CLV:CAC ratio12.5:1 avg

Order Value

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Average order value$40–$80(avg $55)
Refund rate2–6%(avg 4%)

Lifetime Value

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Customer lifetime value$250–$650(avg $400)
Shipping cost %3–6%(avg 4%)

Compare your store to these benchmarks

Drop your Shopify Orders CSV into the CSV Profit Checker or use the Profit Calculator to see how your margins compare to the supplement industry average.

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