Supplements E-commerce Benchmarks
Typical benchmark ranges for online supplement stores. Figures are editorial estimates compiled from public research and practitioner experience — not formal citations or aggregated merchant data.
Want to know how these ranges are sourced and calculated? Read our methodology.
Supplements profit benchmarks — at a glance
Online supplement stores average a 55% gross margin and a 14% net margin, with a typical refund rate of 4% and customer acquisition cost of $32.
These are typical ranges compiled from public e-commerce research, company filings, and practitioner experience — not formal citations. See how these figures are calculated →
Why these numbers look like this
Supplements combine strong 55% gross margins with a 14% net margin — one of the best net-to-gross ratios in e-commerce — because subscription models drive predictable repeat purchases and low 4% refund rates. The hidden cost is FDA compliance: label accuracy, third-party testing, and good manufacturing practices add 5-8% to COGS that most other industries don't face. Brands that nail compliance and retention simultaneously scale profitably because their $400 average CLV dwarfs the $32 acquisition cost.
At a Glance
55%
Avg gross margin
14%
Avg net margin
3.5x
Avg ROAS
$32
Avg CAC
$55
Avg order value
$400
Avg CLV
Profit Margin
View details →ROAS
View details →Customer Acquisition
View details →Order Value
View details →Lifetime Value
View details →Compare your store to these benchmarks
Drop your Shopify Orders CSV into the CSV Profit Checker or use the Profit Calculator to see how your margins compare to the supplement industry average.
Read the full Supplements profit guide
Want the narrative breakdown behind these numbers? See our Supplements store profit margin guide for costs, seasonality, and margin-improvement tactics.
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