Supplements Profit Margin — Benchmarks & Data
Published June 2026 · Industry benchmark data
Supplements Profit Margin Benchmarks
55%
Avg gross margin (40–65%)
14%
Avg net margin (10–20%)
35%
Avg COGS (25–45%)
Online supplement stores typically see gross margins of 40–65% and net margins of 10–20%. The gap between gross and net comes from advertising costs (8–20% of revenue), shipping (3–6%), and refunds (2–6%).
Where the Money Goes
For every $100 in revenue, a typical supplement store keeps about $14 after all costs. COGS takes $35, advertising takes $14, shipping takes $4, and refunds claim $4 of gross revenue before accounting for payment processing fees.
Profit Example
Revenue: $100,000
COGS (35%): -$35,000
Ad spend (14%): -$14,000
Shipping (4%): -$4,000
Refunds (4%): -$4,000
Payment fees (2.9%): -$2,900
Net profit: $40,100 (40.1% margin)
To see your actual numbers, use the CSV Profit Checker with your Shopify data or the Profit Calculator for a quick estimate.
Frequently Asked Questions
What is the average profit margin for supplement stores?
Online supplement stores average 40-65% gross margin and 10-20% net margin. COGS typically runs 25-45% of revenue, with advertising at 8-20%.
What is a good net margin for a supplement store?
A net margin above 20% is strong for supplement stores. The average is 14%. Below 10% indicates you need to review COGS, ad spend, or pricing.
How do I calculate my supplement store profit margin?
Profit margin = (Revenue - COGS - Refunds - Fees - Shipping - Ads) / Revenue. Use our Profit Calculator to plug in your numbers, or the CSV Profit Checker for exact figures from your Shopify data.
What eats into supplement store margins the most?
COGS (25-45%) and advertising (8-20%) are the two largest costs for most supplement stores. Reducing either by even 2-3 percentage points significantly improves profitability.
How can I improve my supplement store margins?
Three levers: reduce COGS by negotiating with suppliers or private-labeling, lower ad costs by building email and social channels, and increase average order value with bundles and upsells.